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Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies

9 Jul 2007

Abstract excerpt

The severe acute respiratory syndrome coronavirus (SARS-CoV) caused a worldwide epidemic in late 2002/early 2003 and a second outbreak in the winter of 2003/2004 by an independent animal-to-human transmission. The GD03 strain, which was isolated from an index patient of the second outbreak, was reported to resist neutralization by the human monoclonal antibodies (hmAbs) 80R and S3.1, which can potently neutralize...

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PMID: 17620608
DOI: 10.1073/pnas.0701000104

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