Article
Effect of the ocular microenvironment in regulating corneal dendritic cell maturation.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jul 2007
Shen Linling, Barabino Stefano, Taylor Andrew W, Dana M Reza
Abstract excerpt
OBJECTIVE: To determine whether the ocular anterior segment (aqueous humor and cornea) actively inhibits dendritic cell (DC) maturation. METHODS: Dendritic cells were injected into syngeneic corneas or conjunctivae, and their surface major histocompatibility complex class II expression in response to the local milieu was assessed using confocal microscopy. Immature DCs were cocultured with corneal supernatant or...
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