Article
Genetic heterogeneity among uterine leiomyomata: insights into malignant progression.
Human molecular genetics - 15 Apr 2007
Hodge Jennelle C, Morton Cynthia C
Abstract excerpt
Uterine leiomyomata (UL), also known as fibroids, are the most common pelvic tumors in women of reproductive age and are the primary indication for hysterectomy in the USA. Many lines of evidence indicate a strong genetic component to the development of these tumors. In fact, approximately 40% of UL have non-random, tumor-specific chromosome abnormalities which have allowed classification into well-defined...
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