Article
Association between PPARGC1A gene polymorphisms and coronary artery disease in a Chinese population.
Clinical and experimental pharmacology & physiology - 1 Oct 2008
Zhang Yan, Xu Weiwei, Li Xiaoyu, Tang Yibo, Xie Peng, Ji Yong, Fan Leming, Chen Qi
Abstract excerpt
Peroxisome proliferrator-activated receptor gamma coactivator-1alpha (PGC-1alpha; PPARGC1A) is a coactivator of the nuclear hormone receptor family that participates in the transcriptional programme of lipid metabolism and oxidative stress implicated in atherogenesis. Therefore, in the present study, we investigated PPARGC1A polymorphisms in the prevalence of coronary artery disease (CAD). A case-control study...
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