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Article

Epistasis between calpain 1 and its inhibitor calpastatin within breeds of cattle.

Genetics - 1 Aug 2007

Barendse W, Harrison B E, Hawken R J, Ferguson D M, Thompson J M, Thomas M B, Bunch R J

Abstract excerpt

The calpain gene family and its inhibitors have diverse effects, many related to protein turnover, which appear to affect a range of phenotypes such as diabetes, exercise-induced muscle injury, and pathological events associated with degenerative neural diseases in humans, fertility, longevity, and postmortem effects on meat tenderness in livestock species. The calpains are inhibited by calpastatin, which binds...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17603104
DOI: 10.1534/genetics.107.074328
PMCID: PMC1950658

Genes

CAPN1
CAST

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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