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Article

Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome.

Journal of the American Society of Nephrology : JASN - 1 Aug 2007

Sellier-Leclerc Anne-Laure, Fremeaux-Bacchi Veronique, Dragon-Durey Marie-Agnès, Macher Marie-Alice, Niaudet Patrick, Guest Geneviève, Boudailliez Bernard, Bouissou François, Deschenes Georges, Gie Sophie, Tsimaratos Michel, Fischbach Michel, Morin Denis, Nivet Hubert, Alberti Corinne, Loirat Chantal

Abstract excerpt

Mutations in factor H (CFH), factor I (IF), and membrane cofactor protein (MCP) genes have been described as risk factors for atypical hemolytic uremic syndrome (aHUS). This study analyzed the impact of complement mutations on the outcome of 46 children with aHUS. A total of 52% of patients had m...

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Share to Complement Factor H
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17599974
DOI: 10.1681/ASN.2006080811

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17599974-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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