Article
Extra copies of chromosomes 16 and X in invasive breast carcinomas are related to aggressive phenotype and poor prognosis.
Journal of clinical pathology - 1 Jul 2007
Nakopoulou Lydia, Panayotopoulou Effie G, Giannopoulou Ioanna, Tsirmpa Ioanna, Katsarou Sophia, Mylona Eleni, Alexandrou Paraskevi, Keramopoulos Antonios
Abstract excerpt
BACKGROUND: Breast cancer is a genetically complex disease, which involves the accumulation of various structural and numerical chromosomal aberrations. AIM: To assess the numerical status of chromosomes 16 and X by interphase cytogenetics, in 114 women with primary invasive breast carcinomas, in relation to clinicopathological parameters, patients' overall survival and indices of cell growth (c-erbB-2,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
