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Article

Dictyostelium gnt15 encodes a protein with similarity to LARGE and plays an essential role in development.

Biochemical and biophysical research communications - 17 Aug 2007

Pang Te-Ling, Wu Chao-Jung, Chen Pin-An, Weng Yi-Lan, Chen Mei-Yu

Abstract excerpt

LARGE is a putative glycosyltransferase found to be mutated in mice with myodystrophy or patients with congenital muscular dystrophy. By homology searches, we identified in the Dictyostelium discoideum genome four open reading frames, i.e. gnt12-15, encoding proteins with sequence similarity to LARGE. Semi-quantitative RT-PCR analysis revealed distinct temporal expression patterns of the four gnt genes throughout...

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PMID: 17588537
DOI: 10.1016/j.bbrc.2007.06.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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