Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects

Abstract excerpt

BACKGROUND: There is much evidence to suggest that risk for common clinical disorders begins in foetal life. Exposure to environmental risk factors however is often not random. Many commonly used indices of prenatal adversity (e.g. maternal gestational stress, gestational diabetes, smoking in pregnancy) are influenced by maternal genes and genetically influenced maternal behaviour. As mother provides the baby...

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