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Article

Analytical and diagnostic characteristics of 11 2nd- and 3rd-generation immunoenzymatic methods for the detection of antibodies to citrullinated proteins.

Clinical chemistry - 1 Aug 2007

Bizzaro Nicola, Tonutti Elio, Tozzoli Renato, Villalta Danilo

Abstract excerpt

BACKGROUND: Measurement of antibodies to citrullinated peptides or proteins (CP) is a new test for the diagnosis of rheumatoid arthritis (RA). We analyzed the analytical characteristics and diagnostic accuracy of commercially available methods. METHODS: We studied 11 commercially available 2nd- and 3rd-generation methods that used various citrullinated antigen substrates: synthetic cyclic peptides, recombinant...

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PMID: 17586589
DOI: 10.1373/clinchem.2007.087569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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