The role of angiotensin-converting enzyme gene insertion/deletion polymorphism for blood pressure regulation in areca nut chewers.

Abstract excerpt

Areca tannin has been suggested as having a blood pressure regulatory effect through its ability to inhibit the pressor response to both angiotensin I and II. As genetic and environmental factors determine the susceptibility and development of diseases and no report has been published concerning the genetic interaction of metabolic effects in areca nut/betel quid (BQ) chewers, it is proposed that the...

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