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Human papillomavirus-16 is integrated in lung carcinomas: a study in Chile

19 Jun 2007

Abstract excerpt

The human papillomavirus (HPV) was detected in 20 (29%) out of 69 lung carcinomas (LCs) in Chile, by PCR and Southern blot, and was more frequently detected in squamous cell carcinoma (SQC) than in adenocarcinomas (46 vs 9%, P=0.001). HPV-16, positive in 11 cases, was the most frequently detected HPV genotype determined by DNA sequencing. HPV-16 E2/E6 ratio, estimated from real-time PCR analysis, was much lower...

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PMID: 17579626
DOI: 10.1038/sj.bjc.6603848

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