Bovine Oocytes with the Potential to Reprogram Somatic Cell Nuclei Have a Unique 23-kDa Protein, Phosphorylated Transcriptionally Controlled Tumor Protein (TCTP)

Abstract excerpt

Despite the long-held assumption that reprogramming factors are present in mammalian oocytes at the second metaphase stage, the molecular nature of these factors is not known. Here, we demonstrated that oocytes with the potential to reprogram somatic cell nuclei have a unique 23-kDa protein, phosphorylated transcriptionally controlled tumor protein (TCTP). Injection of TCTP double-stranded RNA into germinal...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pluripotent Stem Cells Research
• Share to Renal and related cancers
• Share to Reproductive Biology and Fertility