Article
Homogeneous DNA-detection based on the non-enzymatic reactions promoted by target DNA.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry - 1 Jun 2007
Ihara Toshihiro, Mukae Motoko
Abstract excerpt
Much effort has focused on methods for detecting various genetic differences in individuals, including single nucleotide polymorphisms (SNPs). SNP can be characterized as a substitution, insertion, or deletion at a single base position on a DNA strand. There is expected to be on average one SNP for every 1000 bases of the human genome, and some variations located in genes are suspected to alter both the protein...
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