Article
An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Molecular microbiology - 1 Jul 2007
Fraser James S, Merlie John P, Echols Nathaniel, Weisfield Shellie R, Mignot Tâm, Wemmer David E, Zusman David R, Alber Tom
Abstract excerpt
The Myxococcus xanthus FrzS protein transits from pole-to-pole within the cell, accumulating at the pole that defines the direction of movement in social (S) motility. Here we show using atomic-resolution crystallography and NMR that the FrzS receiver domain (RD) displays the conserved switch Tyr102 in an unusual conformation, lacks the conserved Asp phosphorylation site, and fails to bind Mg(2+) or the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.