Article
Neuronal apoptosis in neurodegeneration.
Antioxidants & redox signaling - 1 Aug 2007
Okouchi Masahiro, Ekshyyan Oleksandr, Maracine Magdalena, Aw Tak Yee
Abstract excerpt
Apoptosis mediates the precise and programmed natural death of neurons and is a physiologically important process in neurogenesis during maturation of the central nervous system. However, premature apoptosis and/or an aberration in apoptosis regulation is implicated in the pathogenesis of neurodegeneration, a multifaceted process that leads to various chronic disease states, such as Alzheimer's (AD), Parkinson's...
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