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Article

Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.

Cancer biology & therapy - 1 Jun 2007

Katoh Masaru

Abstract excerpt

Genetic factors, Helicobacter pylori infection, salt over-uptake, decreased vegetable/fruit consumption, smoking, and metabolic syndrome are risk factors of human gastric cancer. Germline mutations of CDH1 gene, and SNPs of PTPN11 (SHP2), TLR4, IL1B, TNFA, BMP6, GDF15 and RUNX3 genes are associat...

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Source

Identifiers

PMID: 17568183
DOI: 10.4161/cbt.6.6.4196

Genes

SFRP1
DKK1
JAG1
JAG2
TLR4
TRAF6
BMP6
CCND1
CCND2
CDH1
FGF20
FGFR2
FOXL1
GDF15
GLI1
IHH
MYC
NLK
NOD1
PTCH1
PTPN11
RUNX3
SHH
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17568183-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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