Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CARD15/NOD2 is required for Peyer's patches homeostasis in mice.

PloS one - 13 Jun 2007

Barreau Frédérick, Meinzer Ulrich, Chareyre Fabrice, Berrebi Dominique, Niwa-Kawakita Michiko, Dussaillant Monique, Foligne Benoit, Ollendorff Vincent, Heyman Martine, Bonacorsi Stéphane, Lesuffleur Thecla, Sterkers Ghislaine, Giovannini Marco, Hugot Jean-Pierre

Abstract excerpt

BACKGROUND: CARD15/NOD2 mutations are associated with susceptibility to Crohn's Disease (CD) and Graft Versus Host Disease (GVHD). CD and GVHD are suspected to be related with the dysfunction of Peyer's patches (PP) and isolated lymphoid follicles (LFs). Using a new mouse model invalidated for Ca...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Homeostasis

Share to Immunoenzyme Techniques

Share to Nod2 Signaling Adaptor Protein

Share to Peyer's Patches

Share to Spleen

Source

Open in PubMed Open full text

Identifiers

PMID: 17565376
DOI: 10.1371/journal.pone.0000523
PMCID: PMC1885825

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17565376-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CARD15/NOD2 is required for Peyer's patches homeostasis in mice.PMID 17565376Read ↗

Functional consequences of NOD2/CARD15 mutations in Crohn disease.Semantic proximity Read ↗

NOD2 mutation and mice: no Crohn's disease but many lessons to learn.Semantic proximity Read ↗

Can NOD2/CARD15 mutations predict intestinal graft-versus-host disease and aid our understanding of Crohn's disease?Semantic proximity Read ↗

NOD2/CARD15 and the Paneth cell: another piece in the genetic jigsaw of inflammatory bowel disease.Semantic proximity Read ↗

NOD2/CARD15 disease associations other than Crohn's disease.Semantic proximity Read ↗

Colonic lymphoid follicles and NOD2/CARD15 mutational status in Crohn's disease.Semantic proximity Read ↗

Functional consequences of NOD2 (CARD15) mutations.Semantic proximity Read ↗

New insights into the pathogenesis of Crohn's disease: are they relevant for therapeutic options?Semantic proximity Read ↗

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses.Semantic proximity Read ↗

Advances in the molecular dissection of inflammatory bowel disease.Semantic proximity Read ↗

[Role of CARD15/Nod2 in the regulation of the host's response to pathogens in patients with Crohn's disease].Semantic proximity Read ↗

[NOD2/CARD15 and Crohn's disease].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.