Article
Coding tandem repeats generate diversity in Aspergillus fumigatus genes.
Eukaryotic cell - 1 Aug 2007
Levdansky Emma, Romano Jacob, Shadkchan Yona, Sharon Haim, Verstrepen Kevin J, Fink Gerald R, Osherov Nir
Abstract excerpt
Genes containing multiple coding mini- and microsatellite repeats are highly dynamic components of genomes. Frequent recombination events within these tandem repeats lead to changes in repeat numbers, which in turn alters the amino acid sequence of the corresponding protein. In bacteria and yeasts, the expansion of such coding repeats in cell wall proteins is associated with alterations in immunogenicity,...
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