Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intragenic tandem repeats generate functional variability.

Nature genetics - 1 Sept 2005

Verstrepen Kevin J, Jansen An, Lewitter Fran, Fink Gerald R

Abstract excerpt

Tandemly repeated DNA sequences are highly dynamic components of genomes. Most repeats are in intergenic regions, but some are in coding sequences or pseudogenes. In humans, expansion of intragenic triplet repeats is associated with various diseases, including Huntington chorea and fragile X synd...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Surface
Share to Genes, Fungal
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Fungal

Share to Molecular Sequence Data

Share to Recombination, Genetic

Share to Saccharomyces cerevisiae

Share to Tandem Repeat Sequences

Source

Open in PubMed Open full text

Identifiers

PMID: 16086015
DOI: 10.1038/ng1618
PMCID: PMC1462868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16086015-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intragenic tandem repeats generate functional variability.PMID 16086015Read ↗

Coding tandem repeats generate diversity in Aspergillus fumigatus genes.Semantic proximity Read ↗

Unstable microsatellite repeats facilitate rapid evolution of coding and regulatory sequences.Semantic proximity Read ↗

To Repeat or Not to Repeat: Repetitive Sequences Regulate Genome Stability in Candida albicans.Semantic proximity Read ↗

Variation in repeat copy number of the <i>Epithelial adhesin 1</i> tandem repeat region leads to variable protein display through multiple mechanismsSemantic proximity Read ↗

Coding repeat instability in the FLO11 gene of Saccharomyces yeasts.Semantic proximity Read ↗

Highly mutable tandem DNA repeats generate a cell wall protein variant more frequent in disease-causing Candida albicans isolates than in commensal isolates.Semantic proximity Read ↗

Real-Time Evolution of a Subtelomeric Gene Family in Candida albicans.Semantic proximity Read ↗

Genome plasticity in Candida albicans is driven by long repeat sequencesSemantic proximity Read ↗

Substitutions of short heterologous DNA segments of intragenomic or extragenomic origins produce clustered genomic polymorphisms.Semantic proximity Read ↗

Architectural groups of a subtelomeric gene family evolve along distinct paths in Candida albicans.Semantic proximity Read ↗

Analysis of microsatellites in 13 hemiascomycetous yeast species: mechanisms involved in genome dynamics.Semantic proximity Read ↗

Functional variability in adhesion and flocculation of yeast megasatellite genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.