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Article

Phylogeography of Rickettsia rickettsii genotypes associated with fatal Rocky Mountain spotted fever.

The American journal of tropical medicine and hygiene - 1 Sept 2014

Paddock Christopher D, Denison Amy M, Lash R Ryan, Liu Lindy, Bollweg Brigid C, Dahlgren F Scott, Kanamura Cristina T, Angerami Rodrigo N, Pereira dos Santos Fabiana C, Brasil Martines Roosecelis, Karpathy Sandor E

Abstract excerpt

Rocky Mountain spotted fever (RMSF), a tick-borne zoonosis caused by Rickettsia rickettsii, is among the deadliest of all infectious diseases. To identify the distribution of various genotypes of R. rickettsii associated with fatal RMSF, we applied molecular typing methods to samples of DNA extracted from formalin-fixed, paraffin-embedded tissue specimens obtained at autopsy from 103 case-patients from seven...

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PMID: 24957541
DOI: 10.4269/ajtmh.14-0146
PMCID: PMC4155566

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