Article
A versatile computational pipeline for bacterial genome annotation improvement and comparative analysis, with Brucella as a use case.
Nucleic acids research - 1 Jan 2007
Yu G X, Snyder E E, Boyle S M, Crasta O R, Czar M, Mane S P, Purkayastha A, Sobral B, Setubal J C
Abstract excerpt
We present a bacterial genome computational analysis pipeline, called GenVar. The pipeline, based on the program GeneWise, is designed to analyze an annotated genome and automatically identify missed gene calls and sequence variants such as genes with disrupted reading frames (split genes) and those with insertions and deletions (indels). For a given genome to be analyzed, GenVar relies on a database containing...
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