Article
Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small-cell lung cancer: results and open issues.
Internal and emergency medicine - 1 Mar 2007
Bencardino K, Manzoni M, Delfanti S, Riccardi A, Danova M, Corazza G R
Abstract excerpt
The medical treatment of non-small-cell lung cancer (NSCLC) has progressively changed since the introduction of "targeted therapy". The development of one of these molecular drug categories, e. g., the epidermal growth factor receptor (EGFR) tyrosine-kinase (TK) selective inhibitors, such as the orally active gefitinib and erlotinib, offers an interesting new opportunity. The clinical response rates obtained with...
Topics
- Carcinoma, Non-Small-Cell Lung
- ErbB Receptors
- Humans
- Lung Neoplasms
- Mutation
- Prognosis
