Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1.

PLoS medicine - 1 Jun 2007

Lee Tae-Hee, Seng Seyha, Sekine Masayuki, Hinton Cimona, Fu Yigong, Avraham Hava Karsenty, Avraham Shalom

Abstract excerpt

BACKGROUND: While vascular endothelial growth factor (VEGF) expression in breast tumors has been correlated with a poor outcome in the pathogenesis of breast cancer, the expression, localization, and function of VEGF receptors VEGFR1 (also known as FLT1) and VEGFR2 (also known as KDR or FLK1), as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunoprecipitation
Share to Lamin Type A
Share to Mammary Neoplasms, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Nuclear Envelope

Share to Transplantation, Heterologous

Share to Vascular Endothelial Growth Factor A

Share to Vascular Endothelial Growth Factor Receptor-1

Source

Open in PubMed Open full text

Identifiers

PMID: 17550303
DOI: 10.1371/journal.pmed.0040186
PMCID: PMC1885450

Genes

NRP1
FLT1
KDR
PGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17550303-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1.PMID 17550303Read ↗

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expressionSemantic proximity Read ↗

Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells.Semantic proximity Read ↗

Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivoSemantic proximity Read ↗

Loss of membranous VEGFR1 expression is associated with an adverse phenotype and shortened survival in breast cancer.Semantic proximity Read ↗

Regression of Human Breast Carcinoma in Nude Mice After Ad <i>sflt</i> Gene Therapy is Mediated by Tumor Vascular Endothelial Cell ApoptosisSemantic proximity Read ↗

Simultaneous, phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody enhances antiangiogenic effects in vivo.Semantic proximity Read ↗

Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy.Semantic proximity Read ↗

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells.Semantic proximity Read ↗

VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells.Semantic proximity Read ↗

Constitutive Endocytosis of VEGFR2 Protects the Receptor against SheddingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.