Article
Transmission of multidrug-resistant HIV-1: 5 years of immunological and virological survey.
AIDS (London, England) - 19 Jun 2007
Delaugerre Constance, Marcelin Anne-Genevieve, Soulié Cathia, Chaix Marie-Laure, Katlama Christine, Girard Pierre-Marie, Calvez Vincent, Morand-Joubert Laurence
Abstract excerpt
Multidrug resistant HIV-1 acquired at the time of primary infection in two patients persisted for at least 5 years with and without treatment. In each patient, only one back mutation to wild-type codon in the protease gene occurred, and that was concomitantly associated with a marked CD4 cell count decrease. In both cases, infection was caused by CCR5 viruses and no rapid clinical progression to AIDS after...
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