Article
Long-term intra-articular administration of recombinant human N-acetylgalactosamine-4-sulfatase in feline mucopolysaccharidosis VI.
Molecular genetics and metabolism - 1 Aug 2007
Auclair Dyane, Hopwood John J, Lemontt Jeffrey F, Chen Lin, Byers Sharon
Abstract excerpt
Degenerative joint disease (DJD) is one aspect of mucopolysaccharidosis VI (MPS VI) pathology that has proven resistant to systemic enzyme replacement therapy (ERT). In this study the effect of repeated intra-articular injections (IA INJ) of recombinant human acetylgalactosamine-4-sulfatase (rh4S...
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