Kin selection and evolution of infectious disease resistance.

doi:10.1111/j.1558-5646.2007.00122.x

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Article

Kin selection and evolution of infectious disease resistance.

Evolution; international journal of organic evolution - 1 Jun 2007

Schliekelman Paul

Abstract excerpt

Discoveries of mutations conferring resistance to infectious diseases have led to increased interest in the evolutionary dynamics of disease resistance. Several recent papers have estimated the historical strength of selection for mutations conferring disease resistance. These studies are based on simple population genetic models that do not take account of factors such as spatial and family structure. Such...

Topics

Alleles
Communicable Diseases
Evolution, Molecular
Family
Humans
Immunity, Innate
Models, Genetic
Receptors, CCR5
Selection, Genetic

Source

Open in PubMed

Identifiers

PMID: 17542839
DOI: 10.1111/j.1558-5646.2007.00122.x

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