Article
Evolution of CC chemokines in teleost fish: a case study in gene duplication and implications for immune diversity.
Immunogenetics - 1 Aug 2007
Peatman Eric, Liu Zhanjiang
Abstract excerpt
Chemokines are a superfamily of cytokines responsible for regulating cell migration under both inflammatory and physiological conditions. CC chemokines are the largest subfamily of chemokines, with 28 members in humans. A subject of intense study in mammalian species, the known functional roles of CC chemokines ligands in both developmental and disease conditions continue to expand. They are also an important...
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