Article
RNA mutations of prox1 detected in human esophageal cancer cells by the shifted termination assay.
Biochemical and biophysical research communications - 27 Jul 2007
Yoshimoto Takanobu, Takahashi Meiko, Nagayama Satoshi, Watanabe Go, Shimada Yutaka, Sakasi Yoshiharu, Kubo Hajime
Abstract excerpt
We have recently reported a novel finding that a candidate tumor suppressor gene prox1 suffered adenosine-to-inosine (A-to-I) RNA mutation without genomic mutation in a subset of human cancer cells and lost its function. Hence, screening of mutations in both cDNA and genomic DNA could be importan...
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