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Article

dXNP, a Drosophila homolog of XNP/ATRX, induces apoptosis via Jun-N-terminal kinase activation.

FEBS letters - 12 Jun 2007

Lee Nam Gon, Hong Yoon Ki, Yu Si Young, Han Seung Yeop, Geum Dongho, Cho Kyoung Sang

Abstract excerpt

XNP/ATRX, a causative gene of X-linked alpha-thalassemia/mental retardation syndrome, encodes an SNF2 family ATPase/helicase protein. To better understand the role of XNP/ATRX in development, we isolated and characterized a Drosophila XNP/ATRX homolog, dXNP, which contains highly conserved SNF2 and helicase domains. Ectopically expressed dXNP induced strong apoptosis in the developing eye and wing, but did not...

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Identifiers

PMID: 17531976
DOI: 10.1016/j.febslet.2007.05.005

Genes

ATRX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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