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Article

Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2008

Brookes K J, Neale B, Xu X, Thapar A, Gill M, Langley K, Hawi Z, Mill J, Taylor E, Franke B, Chen W, Ebstein R, Buitelaar J, Banaschewski T, Sonuga-Barke E, Eisenberg J, Manor I, Miranda A, Oades R D, Roeyers H, Rothenberger A, Sergeant J, Steinhausen H C, Faraone S V, Asherson P

Abstract excerpt

Season of birth (SOB) has been associated with attention deficit hyperactivity disorder (ADHD) in two existing studies. One further study reported an interaction between SOB and genotypes of the dopamine D4 receptor (DRD4) gene. It is important that these findings are further investigated to confirm or refute the findings. In this study, we investigated the SOB association with ADHD in four independent samples...

Topics

Alleles
Attention Deficit Disorder with Hyperactivity
Child
Child, Preschool
Female
Humans
Linkage Disequilibrium
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Parturition

Receptors, Dopamine D4

Seasons

Source

Identifiers

PMID: 17525975
DOI: 10.1002/ajmg.b.30562

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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