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Article

Impact of interleukin-6 promoter polymorphism and serum interleukin-6 level on the acute inflammation and neovascularization stages of patients with Eales' disease.

Molecular vision - 1 Jan 2011

Sen Aditi, Paine Suman Kalyan, Chowdhury Imran Hussain, Mukherjee Amrita, Choudhuri Subhadip, Saha Avijit, Mandal Lakshmi Kanta, Bhattacharya Basudev

Abstract excerpt

PURPOSE: To evaluate the role of interleukin-6 (IL-6) in the inflammatory and proliferative stages of Eales' disease (ED) and to determine the influence of IL-6-174G/C polymorphism in the IL-6 and IL-6-regulated protein expression, as well as the development of ED. METHODS: One hundred and twenty-one patients diagnosed with ED, 223 matched healthy controls, and 16 control patients with macular holes were...

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PMID: 22025890
PMCID: PMC3198485

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