Dedifferentiation phenomena after denervation of mammalian adult vestibular receptors.

Abstract excerpt

The effect of transecting the vestibular nerve on the vestibular sensory epithelium was studied in adult guinea-pigs. When denervation was complete, after fifteen days, the vestibular hair cells began to show morphological features of immaturity. After two months, the majority of hair cells showed a supporting cell phenotype. By four months, both hair cells and supporting cells had become morphologically similar...

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