Article
Mast cell distribution, activation, and phenotype in xanthoma.
Journal of the American Academy of Dermatology - 1 Jun 2007
Matsumoto Masaaki, Kunimitsu Sawa, Wada Kana, Ikeda Mitsunori, Keyama Akira, Kodama Hajime
Abstract excerpt
BACKGROUND: Activated mast cells enhance the uptake of mast cell-derived proteoglycan-low-density lipoprotein complexes by macrophages. OBJECTIVE: We sought to investigate mast cell contribution to the pathogenesis of xanthoma. METHODS: Twenty cases of xanthelasma palpebrarum and 6 cases of tuberous xanthoma lesions were analyzed using immunohistochemical staining. RESULTS: Xanthelasma lesions contained up to...
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