Article
Pharmacogenetic interaction between paraoxonase-1 gene promoter polymorphism C-107T and statin.
Pharmacogenetics and genomics - 1 Jun 2007
Deakin Sara, Guernier Sophie, James Richard W
Abstract excerpt
OBJECTIVE: The aims of this study were to compare the impact of transcription factors, together with statin, on the paraoxonase promoter alleles defined by the C(-107T) polymorphism and to more clearly define regions of the paraoxonase promoter implicated in the actions of transcription factors. METHODS: Expression studies of promoter alleles were performed with reporter gene cassettes transfected into HepG2...
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