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Article

Identification of Cellular Genes Targeted by KSHV-Encoded MicroRNAs

8 May 2007

Abstract excerpt

MicroRNAs (miRNAs) are 19 to 23 nucleotide-long RNAs that post-transcriptionally regulate gene expression. Human cells express several hundred miRNAs which regulate important biological pathways such as development, proliferation, and apoptosis. Recently, 12 miRNA genes have been identified within the genome of Kaposi sarcoma-associated herpesvirus; however, their functions are still unknown. To identify host...

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PMID: 17500590
DOI: 10.1371/journal.ppat.0030065

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