Characterization of Japanese-American men with a single neocortical AD lesion type.

doi:10.1016/j.neurobiolaging.2007.03.026

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Characterization of Japanese-American men with a single neocortical AD lesion type.

Neurobiology of aging - 1 Oct 2008

Petrovitch Helen, Ross G Webster, He Qimei, Uyehara-Lock Jane, Markesbery William, Davis Daron, Nelson James, Masaki Kamal, Launer Lenore, White Lon R

Abstract excerpt

Neocortical neuritic plaques (NP) and neurofibrillary tangles (NFT) are hallmarks of Alzheimer's disease (AD) and usually, both are present. The Honolulu-Asia Aging Study autopsy series includes a significant number of individuals with only one neocortical AD lesion type. These could represent an early phase of the AD process. If so, such individuals would be expected to share other clinical and pathological...

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Characterization of Japanese-American men with a single neocortical AD lesion type.

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