Article
Identification of three novel alleles of HLA-DRB1 and HLA-A in the Brazilian population.
Tissue antigens - 1 Jun 2007
Abdeen H, McErlean C, Moraes M E, Torres M, Campiotto S, Galvão S, Gouvea C, Middleton D
Abstract excerpt
Two human leukocyte antigen (HLA)-DRB1 (HLA-DRB1*1376 and -DRB1*1465) and one HLA-A (HLA-A*2471) novel alleles have been identified in individuals from the Brazilian Bone Marrow Donor Registry. DNA sequencing of exon 2 for HLA-DRB1 alleles showed two and five nucleotide substitutions in -DRB1*1376 and -DRB1*1465, compared with closely related alleles, respectively. These substitutions result in a change of amino...
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