Article
HLA alleles as predisposal factors for postmenopausal osteoporosis in a Greek population.
Tissue antigens - 1 Jun 2007
Douroudis K, Tarassi K, Athanassiades T, Giannakopoulos F, Kominakis A, Thalassinos N, Papasteriades Ch
Abstract excerpt
It is well established that genetic factors play an important role in the pathogenesis of osteoporosis, a common condition characterized by reduced bone mass and increased fracture risk. The major histocompatibility complex in humans, known as human leukocyte antigen (HLA) region, is the most polymorphic human genetic system and it is known as a cluster of genetic markers, associated with several diseases. In...
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