Article
Successful interferon treatment in a patient chronically infected with hepatitis B virus carrying unusual S- (and P-) mutants in the presence of anti-HBs antibodies.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jun 2007
Frider Bernardo, Alessio Analía, Pozzati Marcia, Cuestas María L, Mathet Verónica L, Oubiña José R
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) immune escape mutants with point mutations within the S gene may arise during the natural course of HBV infection, due to a positive selection pressure exerted by the host immune response. Mutations within the immunodominant B and T cell epitopes of hepatitis B...
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