Article
Analysis of the BTNL2 truncating splice site mutation in tuberculosis, leprosy and Crohn's disease.
Tissue antigens - 1 Mar 2007
Johnson C M, Traherne J A, Jamieson S E, Tremelling M, Bingham S, Parkes M, Blackwell J M, Trowsdale J
Abstract excerpt
The region on chromosome 6 encoding the major histocompatibility complex (MHC) is associated with a number of autoimmune and infectious diseases. Primary susceptibility to many of these has been localized to a region containing the human leukocyte antigen (HLA)-DR and -DQ genes. A recent study of sarcoidosis has provided evidence of an independent effect, associated with a truncating single nucleotide...
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