Article
Identification and biochemical characterization of a novel carotenoid oxygenase: elucidation of the cleavage step in the Fusarium carotenoid pathway.
Molecular microbiology - 1 Apr 2007
Prado-Cabrero Alfonso, Estrada Alejandro F, Al-Babili Salim, Avalos Javier
Abstract excerpt
The synthesis of the acidic apo-carotenoid neurosporaxanthin by the fungus Fusarium fujikuroi depends on four enzyme activities: phytoene synthase and carotene cyclase, encoded by the bifunctional gene carRA, a carotene desaturase, encoded by carB, and a postulated cleaving enzyme converting torulene (C(40)) into neurosporaxanthin (C(35)). Based on sequence homology to carotenoid oxygenases, we identified the...
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