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Article

Is the Wisconsin Card Sorting Test a useful neurocognitive endophenotype?

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2007

Kremen William S, Eisen Seth A, Tsuang Ming T, Lyons Michael J

Abstract excerpt

The Wisconsin Card Sorting Test (WCST) has been utilized extensively as a measure of executive function and working memory and as a neurocognitive probe of prefrontal brain function. In studies of psychiatric illness--particularly schizophrenia--it has also been considered to be a cognitive vulnerability marker or endophenotype. Heritability is an important criterion for an endophenotype, but the very few studies...

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Identifiers

PMID: 17492770
DOI: 10.1002/ajmg.b.30527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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