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Article

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.

Blood - 15 Aug 2007

Camaschella Clara, Campanella Alessandro, De Falco Luigia, Boschetto Loredana, Merlini Roberta, Silvestri Laura, Levi Sonia, Iolascon Achille

Abstract excerpt

Inherited microcytic-hypochromic anemias in rodents and zebrafish suggest the existence of corresponding human disorders. The zebrafish mutant shiraz has severe anemia and is embryonically lethal because of glutaredoxin 5 (GRLX5) deletion, insufficient biogenesis of mitochondrial iron-sulfur (Fe/...

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Source

Identifiers

PMID: 17485548
DOI: 10.1182/blood-2007-02-072520

Genes

GLRX5
ALAS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17485548-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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