Article
Relative efficiency of haplotype frequency estimation in sibships and nuclear families compared to unrelated individuals.
Human heredity - 1 Jan 2007
Putter H, Meulenbelt I, van Houwelingen J C
Abstract excerpt
The problem of estimating haplotype frequencies from unphased single nucleotide polymorphism (SNP) genotype data in sibships with and without parents is considered. We focus on the Fisher information of the haplotype frequencies of the parents in order to correctly deal with the dependence of hap...
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