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Article

Linkage and segregation analysis of black and brindle coat color in domestic dogs.

Genetics - 1 Jul 2007

Kerns Julie A, Cargill Edward J, Clark Leigh Anne, Candille Sophie I, Berryere Tom G, Olivier Michael, Lust George, Todhunter Rory J, Schmutz Sheila M, Murphy Keith E, Barsh Gregory S

Abstract excerpt

Mutations of pigment type switching have provided basic insight into melanocortin physiology and evolutionary adaptation. In all vertebrates that have been studied to date, two key genes, Agouti and Melanocortin 1 receptor (Mc1r), encode a ligand-receptor system that controls the switch between synthesis of red-yellow pheomelanin vs. black-brown eumelanin. However, in domestic dogs, historical studies based on...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 1

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Identifiers

PMID: 17483404
DOI: 10.1534/genetics.107.074237
PMCID: PMC1931550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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