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Article

Signature of balancing selection at the MC1R gene in Kunming dog populations.

PloS one - 1 Jan 2013

Wang Guo-dong, Cheng Lu-guang, Fan Ruo-xi, Irwin David M, Tang Shu-sheng, Peng Jian-guo, Zhang Ya-ping

Abstract excerpt

Coat color in dog breeds is an excellent character for revealing the power of artificial selection, as it is extremely diverse and likely the result of recent domestication. Coat color is generated by melanocytes, which synthesize pheomelanin (a red or yellow pigment) or eumelanin (a black or brown pigment) through the pigment type-switching pathway, and is regulated by three genes in dogs: MC1R (melanocortin...

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PMID: 23424634
DOI: 10.1371/journal.pone.0055469
PMCID: PMC3570536

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ASIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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