Article
Assessment of X bends in patients with atypical X chromosome phenotypes.
Annales de genetique - 1 Jan 1991
Munn C A, Wenger S L, Steele M W
Abstract excerpt
Several patients with X chromosome structural abnormalities have been more severely affected clinically than expected. Since bends at Xq13-21 have been associated with inactivation, the authors scored bends retrospectively in 62 patients with X chromosome aneuploidy and 21 cases with structural abnormalities of the X chromosome. They found that patients with 2 X inactivation sites where one X was structurally...
Topics
- Aneuploidy
- Chromosome Deletion
- Dosage Compensation, Genetic
- Female
- Humans
- Male
- Phenotype
- Retrospective Studies
- Sex Chromosome Aberrations
- Turner Syndrome
- X Chromosome