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Article

Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis.

Microbiology (Reading, England) - 1 May 2007

Montanari Sara, Oliver Antonio, Salerno Paola, Mena Ana, Bertoni Giovanni, Tümmler Burkhard, Cariani Lisa, Conese Massimo, Döring Gerd, Bragonzi Alessandra

Abstract excerpt

The high prevalence of hypermutable (mismatch repair-deficient) Pseudomonas aeruginosa strains in patients with cystic fibrosis (CF) is thought to be driven by their co-selection with adaptive mutations required for long-term persistence. Whether the increased mutation rate of naturally hypermutable strains is associated with a biological benefit or cost for the colonization of secondary environments is not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to MutS DNA Mismatch-Binding Protein

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Source

Identifiers

PMID: 17464058
DOI: 10.1099/mic.0.2006/003400-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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