Article
Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene.
Molecular therapy : the journal of the American Society of Gene Therapy - 1 Jul 2007
Miletic Hrvoje, Fischer Yvonne, Litwak Sara, Giroglou Tsanan, Waerzeggers Yannic, Winkeler Alexandra, Li Huongfeng, Himmelreich Uwe, Lange Claudia, Stenzel Werner, Deckert Martina, Neumann Harald, Jacobs Andreas H, von Laer Dorothee
Abstract excerpt
Adult stem cells are promising cellular vehicles for therapy of malignant gliomas as they have the ability to migrate into these tumors and even track infiltrating tumor cells. However, their clinical use is limited by a low passaging capacity that impedes large-scale production. In the present s...
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